Anotace:
Aluminium is abundant in nature, food, or water and thus its exposition is part of everyday life. However, overexposure can result in cellular malfunctions. Therefore, the aim of this study was to investigate the effects of aluminium on eukaryotes, with the use of Schizosaccharomyces pombe as a model organism. Spectrophotometry at OD600, inductively-coupled plasma optical emission spectroscopy (ICP-OES) and microscopy techniques were used to analyse aluminium responses on the living system. Our results revealed that exposition of increasing aluminium concentrations leads to cell growth inhibition in a concentration-dependent manner. Furthermore, our results indicate that the yeast cell is able to eliminate lower aluminium concentration from the cell, while cells surrounded by higher aluminium concentrations lose this ability. Here we also show that high concentrations of aluminium have an impact on cell morphology leading to cell integrity disruption. Findings presented in this study have the ambition to bring more light in an issue of how aluminium mediates impairments of the living organism.