Influence of boundary conditions on stochastic movement of biological molecular motors

Milada Krejčová, Miroslav Holeček

Influence of boundary conditions on stochastic movement of biological molecular motors

Číslo: 2/2018
Periodikum: Applied and Computational Mechanics
DOI: 10.24132/acm.2018.461

Klíčová slova: statistical physics; biomechanics; molecular motors; Fokker-Planck equation; WPE algorithm

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Anotace: The aim of this work is to show the use of statistical physics in biomechanics, especially for modelling a muscle on molecular level. To approximate stochastic (Markovian) evolution in the spatial variable of muscle configuration, we solve the Fokker-Planck equation with the use of the Wang-Peskin-Elston algorithm. The approach is used for numerical simulation in MATLAB of the system time development with different boundary conditions.